All IgG is not equal – the story of afucosylation

Bismillah, alhamdulillah: Antibodies are Y shaped molecules. The head of the Y binds the antigen, such as the spike protein of the SARS-Co-V-2 virus. The head is known as Fab. The stem of the Y triggers the response of the immune system by binding to the right cell or immune fighting proteins called complement. ThisContinue reading “All IgG is not equal – the story of afucosylation”

South African COVID19 Puzzle

Bismillah, alhamdulillah: A South African new lineage of SARS-CoV-2 has changes in the region of the genome that may cause both mono and polyclonal escape ie antibodies from serum are not capable of neutralizing this lineage. The unknown question is what could happen if the UK and South African versions exchange genes. It seems theContinue reading “South African COVID19 Puzzle”

Doxycycline and COVID19

Bismillah, alhamdulillah, it gives me great pleasure to announce the publication of our trial protocol called DOXYCYCLINE ULTRA EARLY TREATMENT TRIAL (DUETT): A RANDOMIZED CONTROLLED TRIAL PROTOCOL FOR THE TREATMENT OF COVID-19 . This has been a great achievement for my fellow colleagues at Rawdat Al Khayl Health Center, Dr Maysaa Ashkanani (First Physician InContinue reading “Doxycycline and COVID19”